Rhabdoviridae

From WikiMD's WELLNESSPEDIA

Rhabdoviridae is a family of viruses in the order Mononegavirales. Viruses within this family have a negative-sense single-stranded RNA genome. The viral particles are enveloped and have a bullet shape with a helical symmetry. The family includes the important human pathogen, Rabies virus, which causes the disease rabies.

Taxonomy[edit]

The family Rhabdoviridae is divided into 20 genera:

Structure and genome[edit]

Rhabdoviridae viruses are enveloped, with bullet shaped geometries. The diameter is around 75 nm. Genomes are linear, around 11-15kb in length. The genome codes for five proteins: nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G), and the RNA dependent RNA polymerase (L).

Replication[edit]

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral G glycoproteins to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. The virus exits the host cell by budding, and tubule-guided viral movement. Humans and mammals serve as the natural host.

Diseases[edit]

Rhabdoviridae includes several notable pathogens of humans and animals, such as the Rabies virus, which causes rabies in mammals, and numerous viruses that infect plants.

See also[edit]

References[edit]


External links[edit]


Stub icon

This WikiMD article can only be edited by registered and verified editors. You can log in or register.

Rhabdoviridae[edit]

Sponsored Health Resource

W8MD weight loss success

W8MD Weight Loss, Sleep & MedSpa

Looking for physician-supervised weight loss, semaglutide, tirzepatide, or GLP-1 receptor agonist options? W8MD helps eligible patients in New York City, Brooklyn, New Jersey, Connecticut, Pennsylvania, Delaware, and greater Philadelphia with medical weight loss, sleep medicine, and long-term maintenance support.

GLP-1 specials: Affordable GLP-1 injections NYC and Philadelphia starting from $29.99/week and up for semaglutide with insurance accepted for qualifying visits, and $45/week and up for tirzepatide with insurance accepted for qualifying visits. Self-pay options start from $59.99/week and up for semaglutide and $69.99/week and up for tirzepatide.

Book a W8MD appointment · View GLP-1 specials

Paid promotional message. Eligibility, pricing, insurance coverage, medication availability, and results vary. Medical evaluation required.

Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Retrieved from "https://wikimd.org/index.php?title=Rhabdoviridae&oldid=6618320"