O-4210

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Synthetic opioid analgesic


O-4210 is a synthetic opioid analgesic that was developed in the mid-20th century. It is part of a class of compounds known for their potent analgesic properties, which are primarily used in the management of severe pain.

Chemical Structure[edit | edit source]

Chemical structure of O-4210

O-4210 is chemically related to other opioids, sharing a similar core structure that is characteristic of this class of drugs. The molecular structure of O-4210 includes a phenylpiperidine moiety, which is a common feature in many synthetic opioids. This structural component is crucial for the compound's interaction with the opioid receptors in the central nervous system.

Pharmacology[edit | edit source]

O-4210 acts primarily as an agonist at the μ-opioid receptors, which are responsible for its analgesic effects. Activation of these receptors leads to a decrease in the perception of pain, as well as a reduction in the emotional response to pain. Like other opioids, O-4210 can also produce side effects such as sedation, respiratory depression, and euphoria.

Medical Use[edit | edit source]

The primary use of O-4210 is in the management of severe pain, particularly in cases where other analgesics are ineffective. It is typically administered in a controlled medical setting due to its potency and potential for abuse. The drug's efficacy in pain management makes it a valuable tool in palliative care and in the treatment of chronic pain conditions.

Side Effects[edit | edit source]

Common side effects of O-4210 include nausea, vomiting, constipation, and dizziness. More serious side effects can include respiratory depression, which can be life-threatening if not managed properly. Long-term use of O-4210 can lead to the development of tolerance, physical dependence, and addiction.

Legal Status[edit | edit source]

Due to its potential for abuse and addiction, O-4210 is classified as a controlled substance in many countries. Its use is strictly regulated, and it is typically only available by prescription from a licensed healthcare provider.

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Contributors: Prab R. Tumpati, MD