OR10A2

OR10A2 is a gene that encodes the olfactory receptor protein, OR10A2. This protein is a member of the olfactory receptor family, which is involved in the detection of smell. The OR10A2 gene is located on chromosome 1, specifically at 1q44.

Function

The olfactory receptor proteins, such as OR10A2, are responsible for detecting and identifying a wide range of odors. These proteins are located in the olfactory epithelium, a specialized tissue inside the nose that is involved in smell. When an odor molecule binds to an olfactory receptor, it triggers a signal that is sent to the brain, allowing us to perceive the smell.

Clinical Significance

Mutations in the OR10A2 gene have been associated with a reduced ability to smell certain odors. For example, a study found that individuals with a specific mutation in this gene were unable to detect the smell of androstadienone, a compound found in male sweat that is thought to act as a pheromone.

In addition, variations in the OR10A2 gene may also influence food preferences. A study found that individuals with certain variants of this gene were more likely to dislike cilantro, suggesting that our genes may play a role in shaping our dietary habits.

See Also

• Olfactory receptor
• Olfactory epithelium
• Androstadienone
• Cilantro