OR10G4

OR10G4 is a gene that encodes a protein in humans. It is also known as Olfactory Receptor Family 10 Subfamily G Member 4. This gene is part of the olfactory receptor family, which is the largest gene family in the genome. The olfactory receptors are G protein-coupled receptors that play a role in the detection of odor molecules.

Function

The OR10G4 gene is a member of the olfactory receptor family of genes. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes.

Gene

The OR10G4 gene is located on chromosome 1 (1q44). It spans about 1.1 kilobases and consists of 1 exon. The OR10G4 gene produces a mRNA molecule, which has a length of 1018 bases.

Protein

The protein encoded by the OR10G4 gene is a member of the large family of olfactory receptors. The protein has 7 transmembrane domains, a characteristic of the G protein-coupled receptors. The protein is believed to be located in the cell membrane, where it interacts with odorant molecules to initiate a signal transduction pathway that leads to the perception of smell.

Clinical significance

The role of OR10G4 in disease is not well understood. However, given its role in olfaction, it is possible that mutations in this gene could contribute to conditions such as anosmia (loss of the sense of smell).

See also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia

References

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