OR10P1

OR10P1 is a gene that encodes a protein in the olfactory receptor family. This family is responsible for the detection of odor molecules and the transduction of odorant signals. The OR10P1 gene is specifically involved in the detection of certain odorants.

Function

The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Clinical significance

Variations in the OR10P1 gene have been associated with differences in the perception of specific odors. For example, a study published in the journal Chemical Senses found that individuals with certain variants of the OR10P1 gene were more sensitive to the smell of androstadienone, a compound found in male sweat.

See also

• Olfactory receptor
• G protein-coupled receptor
• Androstadienone

References

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