OR51E1
OR51E1 is a gene that encodes a protein in humans. This protein is a member of the olfactory receptor family, a class of G protein-coupled receptors (GPCRs) that are involved in the detection of smell. The OR51E1 gene is also known as olfactory receptor 51E1.
Function[edit | edit source]
The OR51E1 protein is expressed in the olfactory epithelium, where it is thought to play a role in the detection of odorants. It is also expressed in other tissues, including the prostate, breast, and skin, suggesting that it may have additional functions beyond olfaction.
Clinical significance[edit | edit source]
Alterations in the OR51E1 gene have been associated with various diseases. For example, overexpression of OR51E1 has been observed in prostate cancer, suggesting that it may play a role in the development or progression of this disease. In addition, mutations in the OR51E1 gene have been linked to congenital anosmia, a condition characterized by the inability to perceive odors.
Research[edit | edit source]
Research on OR51E1 is ongoing, with studies investigating its role in disease and its potential as a therapeutic target. For example, some studies are exploring the possibility of using OR51E1 as a biomarker for prostate cancer, while others are investigating the role of OR51E1 in skin health and disease.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD