OR6S1

OR6S1 is a gene that in humans encodes the olfactory receptor, family 6, subfamily S, member 1. It is also known as olfactory receptor OR6-16. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.

Function

Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Gene

The OR6S1 gene is located on chromosome 1, specifically at 1q44. The gene spans approximately 1.1 kilobases and consists of a single coding exon. The exact function of the encoded protein, like that of other members of the olfactory receptor family, is not known. However, it is believed to play a role in olfaction.

Clinical significance

While the specific role of OR6S1 in disease has not been fully elucidated, olfactory receptors in general have been implicated in various diseases, including neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, as well as cancer.

See also

• Olfactory receptor
• G protein-coupled receptor
• Chromosome 1 (human)

References

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