Octamoxin

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Octamoxin is an monoamine oxidase inhibitor (MAOI) that was developed in the 1960s for the treatment of depression. It is a non-selective and irreversible inhibitor of the enzyme monoamine oxidase (MAO).

Etymology[edit | edit source]

The term "Octamoxin" is derived from the chemical structure of the compound, which contains eight carbon atoms (from the Latin octo, meaning "eight") and an amine group (from the Arabic al-'anmā, meaning "the bleach").

Pharmacology[edit | edit source]

Octamoxin works by inhibiting the action of monoamine oxidase, an enzyme that breaks down monoamines in the body. By inhibiting this enzyme, Octamoxin increases the levels of monoamines such as serotonin, norepinephrine, and dopamine in the brain, which can help to alleviate symptoms of depression.

Clinical Use[edit | edit source]

Octamoxin was used in the 1960s as a treatment for depression. However, it has largely been replaced by newer and safer MAOIs due to its potential for serious side effects and interactions with other drugs.

Side Effects[edit | edit source]

The side effects of Octamoxin can include hypertension, insomnia, dizziness, and nausea. In rare cases, it can also cause a serious condition known as serotonin syndrome, which can be life-threatening if not treated promptly.

Related Terms[edit | edit source]

Octamoxin Resources
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Contributors: Prab R. Tumpati, MD