Octodrine

Octodrine is a stimulant drug whose chemical name is dimethylhexylamine (DMHA). It was originally used as a nasal decongestant in the mid-20th century but has recently gained popularity as a dietary supplement for its supposed energy-boosting effects.

History

Octodrine was first synthesized in the 1940s and was marketed as a pharmaceutical drug under the trade name Amidrine for the treatment of nasal congestion. It was available as an over-the-counter medication until the 1970s when it was removed from the market due to lack of evidence supporting its efficacy and safety.

Pharmacology

Octodrine is a sympathomimetic amine, which means it mimics the action of the body's sympathetic nervous system. It is believed to increase levels of norepinephrine in the body, which can increase heart rate and blood pressure. However, the exact mechanism of action of octodrine is not fully understood.

Use in Dietary Supplements

In recent years, octodrine has been used in dietary supplements, particularly pre-workout and weight-loss products, for its supposed energy-boosting and appetite-suppressing effects. However, there is little scientific evidence to support these claims, and the safety and efficacy of octodrine as a dietary supplement are not well-studied.

Health Risks

The use of octodrine, particularly in high doses or in combination with other stimulants, can lead to a number of health risks. These include increased heart rate and blood pressure, which can increase the risk of heart attack and stroke. Other potential side effects include anxiety, tremors, and insomnia.

Legal Status

In many countries, including the United States, octodrine is not approved for use in dietary supplements. However, it is often found in such products, sometimes listed under other names such as DMHA.

See Also

• Dietary supplement
• Sympathomimetic drug
• Norepinephrine

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