Oenanthotoxin

Oenanthotoxin is a toxin found in plants of the Apiaceae family, such as hemlock water-dropwort (Oenanthe crocata) and water fennel (Oenanthe aquatica). It is a potent neurotoxin that can cause severe poisoning in humans and animals.

Chemical Structure

Oenanthotoxin is a polyacetylene compound with a unique structure. It contains a cyclohexene ring and a butenolide moiety, which are connected by a polyene chain. The compound is highly unsaturated, which contributes to its toxicity.

Toxicity

Oenanthotoxin is a potent neurotoxin that acts by blocking the neurotransmitter gamma-aminobutyric acid (GABA) in the central nervous system. This leads to symptoms such as convulsions, tremors, and eventually respiratory failure. In severe cases, oenanthotoxin poisoning can be fatal.

Treatment

Treatment for oenanthotoxin poisoning is primarily supportive. This includes decontamination to remove the toxin from the body, symptomatic treatment to manage symptoms, and intensive care for severe cases. There is currently no specific antidote for oenanthotoxin.

See Also

• Cicutoxin
• Coniine
• Poisonous plants

Oenanthotoxin Resources
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