Orf (animal disease)

Orf is a contagious zoonotic disease affecting sheep and goats, caused by the Orf virus, a member of the Parapoxvirus genus within the Poxviridae family. It is also known as contagious ecthyma, contagious pustular dermatitis, scabby mouth, or sore mouth. Orf primarily affects the skin and mucous membranes of the lips, mouth, and face, leading to the formation of pustular and scabby lesions. While it is primarily an animal health concern, Orf can be transmitted to humans, particularly those in close contact with infected animals, leading to similar skin lesions.

Transmission and Symptoms

Orf virus is transmitted through direct contact with the lesions of infected animals or indirectly through contact with contaminated fomites. The disease is characterized by the appearance of papules, vesicles, pustules, and scabs on the lips, around the mouth, and sometimes on the nostrils, eyes, and ears of affected animals. In severe cases, it can lead to secondary bacterial infections, weight loss due to reduced feeding, and in rare instances, death, especially in young lambs.

In humans, Orf manifests as painful, red nodules on the hands, arms, or face, which develop into blisters and then scab over. The disease is self-limiting and usually resolves within 6 to 8 weeks without treatment.

Diagnosis and Treatment

Diagnosis of Orf is primarily based on clinical signs and symptoms, supported by laboratory tests such as polymerase chain reaction (PCR) for viral DNA, electron microscopy, and virus isolation. There is no specific antiviral treatment for Orf; management focuses on supportive care to relieve symptoms and prevent secondary infections. In animals, this may include the application of topical antiseptics and antibiotics. Vaccination is available for animals and is recommended in endemic areas or for flocks with a history of the disease.

Prevention

Preventive measures include good hygiene practices, isolation of affected animals, and vaccination. Personal protective equipment (PPE) should be worn by individuals handling infected animals or their tissues to prevent human transmission.

Public Health Implications

Orf poses a risk to public health, particularly for farmers, veterinarians, and others in close contact with sheep and goats. Education on the risks associated with Orf and the importance of preventive measures is crucial to reduce the incidence of the disease in both animals and humans.

‎

---

Translate: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, தமிழ், తెలుగు, Urdu, ಕನ್ನಡ, Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, বাংলা
European español, Deutsch, français, Greek, português do Brasil, polski, română, русский, Nederlands, norsk, svenska, suomi, Italian
Middle Eastern & African عربى, Turkish, Persian, Hebrew, Afrikaans, isiZulu, Kiswahili,
Other Bulgarian, Hungarian, Czech, Swedish, മലയാളം, मराठी, ਪੰਜਾਬੀ, ગુજરાતી, Portuguese, Ukrainian