Ormond's disease

From WikiMD's Wellness Encyclopedia

Ormond's Disease, also known as Retroperitoneal Fibrosis, is a rare disorder characterized by the development of fibrous tissue in the area behind the stomach and intestines, known as the retroperitoneal space. This fibrous tissue often encases the ureters, leading to a variety of urinary symptoms.

Etiology[edit | edit source]

The exact cause of Ormond's Disease is unknown. However, it is believed to be associated with certain autoimmune disorders, such as rheumatoid arthritis and systemic lupus erythematosus. It may also be triggered by certain medications, infections, or exposure to specific toxins.

Symptoms[edit | edit source]

The symptoms of Ormond's Disease are often nonspecific and may include abdominal pain, back pain, and unintentional weight loss. As the disease progresses, it may lead to urinary tract obstruction, resulting in symptoms such as frequent urination, urinary urgency, and blood in the urine.

Diagnosis[edit | edit source]

Diagnosis of Ormond's Disease typically involves imaging studies, such as computed tomography (CT) scans or magnetic resonance imaging (MRI). These can reveal the presence of fibrous tissue in the retroperitoneal space. In some cases, a biopsy may be performed to confirm the diagnosis.

Treatment[edit | edit source]

Treatment for Ormond's Disease typically involves managing the symptoms and preventing further progression of the disease. This may include medications to reduce inflammation and slow the growth of fibrous tissue, as well as surgical procedures to relieve urinary tract obstruction.

Prognosis[edit | edit source]

The prognosis for individuals with Ormond's Disease varies. Some individuals may experience a slow progression of the disease with manageable symptoms, while others may experience rapid progression leading to severe urinary tract obstruction and kidney damage.

See Also[edit | edit source]

NIH genetic and rare disease info[edit source]

Ormond's disease is a rare disease.





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Contributors: Prab R. Tumpati, MD