Osaterone
A synthetic steroid used in veterinary medicine
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Osaterone is a synthetic steroid used primarily in veterinary medicine for the treatment of benign prostatic hyperplasia in dogs. It is a steroidal antiandrogen, which means it works by blocking the effects of androgens (male hormones) in the body.
Mechanism of Action[edit | edit source]
Osaterone acts as an antiandrogen by competing with dihydrotestosterone (DHT) for binding to androgen receptors in the prostate gland. This reduces the stimulatory effects of androgens on the prostate, leading to a decrease in prostate size and alleviation of symptoms associated with prostatic hyperplasia.
Uses in Veterinary Medicine[edit | edit source]
Osaterone is specifically used in the treatment of benign prostatic hyperplasia in male dogs. This condition is common in older, intact male dogs and can lead to urinary and defecatory difficulties. By reducing the size of the prostate, osaterone helps to relieve these symptoms and improve the quality of life for affected animals.
Pharmacokinetics[edit | edit source]
Osaterone is administered orally and is well absorbed from the gastrointestinal tract. It undergoes hepatic metabolism and is excreted primarily in the feces. The drug has a relatively long half-life, allowing for once-daily dosing in dogs.
Side Effects[edit | edit source]
Common side effects of osaterone in dogs include mild gastrointestinal upset, such as vomiting or diarrhea. In some cases, changes in behavior or appetite may occur. It is important to monitor dogs for any adverse reactions during treatment.
Chemical Structure[edit | edit source]
Osaterone is a steroidal compound with a complex ring structure typical of many hormones. Its chemical structure is similar to that of other steroidal antiandrogens, allowing it to effectively compete with natural androgens for receptor binding.
Related pages[edit | edit source]
Osaterone
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