Ovandrotone

Ovandrotone is a synthetic, steroidal antiandrogen (AA) that was never marketed. It is an androgen receptor (AR) antagonist and was studied in the treatment of benign prostatic hyperplasia (BPH) in the 1980s.

Pharmacology

Ovandrotone acts as a selective antagonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT). It has been found to possess approximately the same affinity for the AR as the potent androgen DHT.

Medical uses

Ovandrotone was studied in the treatment of benign prostatic hyperplasia (BPH), a condition in which the prostate gland becomes enlarged, causing problems with urination. However, it was never marketed for this or any other indication.

See also

• List of antiandrogens
• List of steroidal antiandrogens

References

Ovandrotone Resources
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