Ovandrotone albumin
Ovandrotone albumin is a protein that is encoded by the OVA gene in humans. It is a member of the serpin family of proteins, which are involved in various biological processes such as coagulation, complement activation, fibrinolysis, angiogenesis, inflammation, and tumor suppression.
Etymology[edit | edit source]
The term "Ovandrotone" is derived from the Latin "ovum", meaning "egg", and "andro", meaning "man". The "tone" suffix indicates that it is a type of hormone. The term "albumin" is derived from the Latin "albus", meaning "white", and refers to the color of the protein in its pure form.
Function[edit | edit source]
Ovandrotone albumin is a serine protease inhibitor (serpin) that functions as a tumor suppressor by inhibiting the activity of certain proteases that are involved in cancer progression. It is also involved in the regulation of angiogenesis, the process by which new blood vessels are formed from pre-existing ones.
Clinical significance[edit | edit source]
Mutations in the OVA gene can lead to the development of various types of cancer, including ovarian cancer, breast cancer, and lung cancer. In addition, overexpression of ovandrotone albumin has been associated with poor prognosis in patients with these types of cancer.
See also[edit | edit source]
References[edit | edit source]
Ovandrotone albumin Resources | |
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