Oxanamide

Oxanamide

Oxanamide is a chemical compound used in the field of pharmacology. It is a sedative and hypnotic drug that was patented in the 1960s. Oxanamide is a member of the class of drugs known as nonbenzodiazepines, which are used primarily as sleep aids.

History

Oxanamide was first synthesized and patented in the 1960s by the pharmaceutical company Upjohn. It was developed as part of a series of nonbenzodiazepine sedatives, which also included glutethimide and methyprylon. However, unlike these other drugs, oxanamide did not achieve widespread use.

Pharmacology

As a nonbenzodiazepine, oxanamide acts on the GABA receptor, a type of neurotransmitter receptor in the brain. It enhances the effect of the neurotransmitter GABA, which inhibits the activity of the nervous system. This results in a calming effect, which can help to induce sleep.

Medical Use

Oxanamide is used primarily as a sleep aid. It can be used to treat insomnia, a condition characterized by difficulty falling asleep or staying asleep. However, due to its potential for addiction and tolerance, it is not typically used as a first-line treatment for this condition.

Side Effects

Like other sedatives, oxanamide can cause a number of side effects. These can include drowsiness, dizziness, and confusion. In more severe cases, it can cause respiratory depression, a condition in which breathing becomes dangerously slow or shallow.

See Also

• Nonbenzodiazepines
• GABA receptor
• Insomnia

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