Oxathiapiprolin
Oxathiapiprolin is a fungicide used in agriculture to control a wide range of plant pathogens. It is particularly effective against oomycetes, a group of fungi-like organisms that cause serious diseases in many crops. Oxathiapiprolin was first registered for use in the United States in 2016.
Chemistry[edit | edit source]
Oxathiapiprolin is a member of the piperidinyl thiazole isoxazoline class of fungicides. It has the molecular formula C15H19F2N3O2S and a molecular weight of 349.4 g/mol. The compound is a white to off-white powder that is not soluble in water.
Mode of Action[edit | edit source]
Oxathiapiprolin inhibits the cellular respiration of oomycetes by binding to the oxysterol binding protein (OSBP), a critical protein in the pathogen's life cycle. This binding disrupts the pathogen's ability to infect the plant, effectively stopping the disease in its tracks.
Uses[edit | edit source]
Oxathiapiprolin is used to control a variety of oomycete diseases, including downy mildew, late blight, and white rust. It can be applied to a wide range of crops, including vegetables, fruits, ornamentals, and turfgrass.
Safety[edit | edit source]
The EPA has classified oxathiapiprolin as a Group E chemical, which means it is not likely to be a human carcinogen. However, like all pesticides, it should be used with caution and according to label instructions to minimize risks to human health and the environment.
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD