Oxidoreductase

Oxidoreductase is a class of enzymes that catalyze the transfer of electrons from one molecule (the oxidant) to another (the reductant). This process is known as oxidation-reduction or redox. Oxidoreductases are classified under EC 1 in the Enzyme Commission number system.

Function

Oxidoreductases play a crucial role in the body's metabolism. They are involved in energy production, the breakdown of food into usable components, and the elimination of harmful substances. They are also involved in the body's immune response, helping to kill bacteria and other pathogens.

Classification

Oxidoreductases are classified into several subclasses based on the type of reaction they catalyze:

• EC 1.1 includes oxidoreductases that act on the CH-OH group of donors (such as alcohol dehydrogenase)
• EC 1.2 includes oxidoreductases that act on the aldehyde or oxo group of donors
• EC 1.3 includes oxidoreductases that act on the CH-CH group of donors (such as fatty acid desaturases)
• EC 1.4 includes oxidoreductases that act on the CH-NH2 group of donors (such as monoamine oxidase)
• EC 1.5 includes oxidoreductases that act on CH-NH group donors
• EC 1.6 includes oxidoreductases that act on NADH or NADPH
• EC 1.7 includes oxidoreductases that act on other nitrogenous compounds as donors
• EC 1.8 includes oxidoreductases that act on a sulfur group of donors
• EC 1.9 includes oxidoreductases that act on a heme group of donors
• EC 1.10 includes oxidoreductases that act on diphenols and related substances as donors
• EC 1.11 includes oxidoreductases that act on peroxide as an acceptor (such as peroxidases)
• EC 1.12 includes oxidoreductases that act on hydrogen as donors
• EC 1.13 includes oxidoreductases that act on single donors with incorporation of molecular oxygen (incorporating 2 atoms of oxygen)
• EC 1.14 includes oxidoreductases that act on paired donors with incorporation of molecular oxygen
• EC 1.15 includes oxidoreductases that act on superoxide radicals as acceptors
• EC 1.16 includes oxidoreductases that act on metal ions as donors
• EC 1.17 includes oxidoreductases that act on CH or CH2 groups
• EC 1.18 includes oxidoreductases that act on iron-sulfur proteins as donors
• EC 1.19 includes oxidoreductases that act on reduced flavodoxin as a donor
• EC 1.20 includes oxidoreductases that act on phosphorus or arsenic in donors
• EC 1.21 includes oxidoreductases that act on X-H and Y-H to form an X-Y bond

See also

• Redox
• Enzyme Commission number
• Metabolism
• Enzyme

Oxidoreductase Resources
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