P-Chloro-o-toluidine

P-Chloro-o-toluidine is an organic compound that belongs to the class of chemical substances known as chloroanilines. It is a derivative of toluidine and is characterized by the presence of a chlorine atom and a methyl group on the benzene ring of the aniline structure.

Chemical Structure and Properties

P-Chloro-o-toluidine has the chemical formula C₇H₈ClN. It is a light yellow crystalline solid at room temperature. The compound is slightly soluble in water, but it is more soluble in organic solvents such as ethanol and acetone.

Synthesis

P-Chloro-o-toluidine can be synthesized through the electrophilic aromatic substitution of o-toluidine with chlorine. The reaction is typically carried out in the presence of a Lewis acid catalyst such as aluminium chloride.

Uses

P-Chloro-o-toluidine is primarily used in the synthesis of other organic compounds. It is a key intermediate in the production of certain dyes, pesticides, and pharmaceuticals.

Health Effects

Exposure to P-Chloro-o-toluidine can have serious health effects. It is classified as a carcinogen by the International Agency for Research on Cancer (IARC). Long-term exposure can lead to bladder cancer and other health problems.

Safety and Handling

Due to its toxic nature, P-Chloro-o-toluidine should be handled with care. Protective clothing, gloves, and eye protection should be worn when handling this compound. In case of exposure, seek immediate medical attention.

See Also

• Aniline
• Toluidine
• Chloroanilines
• Carcinogen