PB-22
PB-22 is a synthetic cannabinoid that is used as an active ingredient in synthetic cannabis products. It was first identified in 2013 in samples of synthetic cannabis products sold in Japan. PB-22 is an analog of JWH-018 which has a quinolinyl group, instead of a naphthoyl group. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Chemistry[edit | edit source]
PB-22 is a derivative of JWH-018, but instead of a naphthoyl group, it has a quinolinyl group. The structure of PB-22 is related to that of other synthetic cannabinoids, including AM-2201, AM-694, AM-1241, and AM-2233. It is a white, crystalline powder that is soluble in organic solvents.
Pharmacology[edit | edit source]
The pharmacological properties of PB-22 are not well-studied. However, it is known to act as a potent agonist for the CB1 receptor, with a Ki of 5.2 nM. This makes it roughly equivalent in potency to JWH-018, although the effects in humans are not known.
Legal status[edit | edit source]
PB-22 is a Schedule I controlled substance in the United States, and is also controlled in many other countries. It is illegal to manufacture, distribute, or possess PB-22 in these jurisdictions.
See also[edit | edit source]
PB-22 Resources | |
---|---|
|
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD