PF-05105679

PF-05105679 is a chemical compound that is classified as a pharmacological agent. It is a potent and selective TRPA1 antagonist, which is a type of transient receptor potential channel involved in the sensation of pain. PF-05105679 is currently under investigation for its potential therapeutic applications in the treatment of pain and other conditions.

Chemical Structure

PF-05105679 is a small molecule with a complex chemical structure. Its systematic name is 2-[[2-(2-methylpropoxy)phenyl]methyl]-3-(trifluoromethyl)-4(1H)-quinolinone. This name is derived from the International Union of Pure and Applied Chemistry (IUPAC) nomenclature system, which provides a standard method for naming chemical substances.

Pharmacology

PF-05105679 acts as an antagonist of the TRPA1 channel, which is a member of the transient receptor potential channel family. These channels are involved in various physiological processes, including the sensation of pain. By blocking the activity of TRPA1, PF-05105679 has the potential to reduce pain signals.

Clinical Trials

PF-05105679 has been investigated in clinical trials for its potential therapeutic applications. These trials have primarily focused on the compound's potential use in the treatment of pain. However, the results of these trials have not yet led to the approval of PF-05105679 for medical use.

Potential Therapeutic Applications

The primary potential therapeutic application of PF-05105679 is in the treatment of pain. This is due to its activity as a TRPA1 antagonist, which could potentially reduce pain signals. Other potential applications could include the treatment of conditions related to TRPA1 activity, such as certain types of inflammation and respiratory disorders.

See Also

• Transient receptor potential channel
• Pain
• Pharmacology
• Clinical trial