PHF3

PHF3 (Plant Homeodomain Finger 3) is a protein that in humans is encoded by the PHF3 gene. This protein is a member of the PHD finger protein family and is known to play a crucial role in cellular biology and genetics.

Function

PHF3 protein is a transcription factor that has been implicated in the regulation of cell cycle and cell differentiation. It is known to interact with other proteins and DNA to control the expression of specific genes. The PHF3 protein contains a PHD finger domain, which is a common feature of proteins involved in chromatin remodeling.

Clinical Significance

Mutations in the PHF3 gene have been associated with various human diseases, including certain types of cancer. For example, studies have shown that overexpression of PHF3 is associated with poor prognosis in lung cancer and breast cancer. Further research is needed to fully understand the role of PHF3 in disease development and progression.

Research

Research on PHF3 is ongoing, with scientists aiming to better understand its function and potential role in disease. Current research focuses on the protein's role in cell cycle regulation, its interactions with other proteins, and its potential as a therapeutic target in cancer treatment.

See Also

• PHD finger protein
• Transcription factor
• Cell cycle
• Cell differentiation
• Chromatin remodeling