PSN-375,963

PSN-375,963 is a drug that acts as a serotonin agonist. It is specifically a 5-HT4 receptor agonist, and it has been researched for its potential use in the treatment of gastrointestinal disorders, although it has not been marketed for medical use.

Pharmacology

PSN-375,963 is a potent and selective 5-HT4 receptor agonist. The 5-HT4 receptor is one of the several different subtypes of the serotonin receptor that are found in the gastrointestinal tract, among other locations in the body. Activation of this receptor by PSN-375,963 can stimulate the release of acetylcholine, which in turn stimulates muscle contractions in the gastrointestinal tract.

Clinical significance

The potential clinical applications of PSN-375,963 are primarily related to its effects on the gastrointestinal tract. It has been suggested that it could be used to treat conditions such as irritable bowel syndrome and gastroesophageal reflux disease, although further research is needed to confirm its efficacy and safety for these uses.

See also

• 5-HT4 receptor
• Serotonin receptor agonist
• Gastrointestinal tract

References

PSN-375,963 Resources
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