Papillary collecting duct

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Papillary Collecting Duct
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Papillary Collecting Duct, also known as Bellini duct, is a part of the kidney's collecting duct system. It plays a crucial role in the urinary system by channeling urine from the nephron to the renal pelvis.

Structure[edit | edit source]

The papillary collecting duct is located in the medulla of the kidney. It is formed by the convergence of multiple cortical collecting ducts. These ducts are lined with epithelial cells that are responsible for the reabsorption of water and electrolytes, as well as the secretion of hydrogen ions and potassium.

Function[edit | edit source]

The primary function of the papillary collecting duct is to transport urine from the distal convoluted tubule to the renal pelvis. During this process, the duct further concentrates the urine by reabsorbing water under the influence of antidiuretic hormone (ADH). This concentration process is essential for maintaining the body's fluid balance and electrolyte homeostasis.

Clinical Significance[edit | edit source]

Disorders of the papillary collecting duct can lead to various renal diseases. One such condition is collecting duct carcinoma, a rare and aggressive form of kidney cancer that originates in the collecting ducts. Symptoms may include hematuria, flank pain, and a palpable mass in the abdomen.

Diagnosis and Treatment[edit | edit source]

Diagnosis of collecting duct disorders often involves imaging studies such as ultrasound, CT scan, or MRI, along with biopsy for histological examination. Treatment options vary depending on the specific condition but may include surgery, chemotherapy, or radiation therapy for malignancies.

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Contributors: Prab R. Tumpati, MD