Pecilocin

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Pecilocin


Pecilocin is a naturally occurring psychedelic compound of the tryptamine class. It is found in most species of the Psilocybe genus, commonly known as "magic mushrooms". Pecilocin is a prodrug that is converted into the pharmacologically active compound psilocin in the body. This conversion is typically accomplished by the liver.

Chemistry[edit | edit source]

Pecilocin is a member of the tryptamine class, which also includes other psychedelic substances such as DMT and LSD. It is structurally similar to the neurotransmitter serotonin, which is why it has psychoactive effects. The compound is a prodrug, meaning it is inactive until it is metabolically converted into the active compound psilocin.

Pharmacology[edit | edit source]

Once ingested, pecilocin is rapidly converted into psilocin by the liver. Psilocin then acts on the serotonin receptors in the brain, particularly the 5-HT2A receptor. This receptor is involved in the regulation of mood, anxiety, and perception, which is why the ingestion of pecilocin can lead to profound changes in these areas.

Effects[edit | edit source]

The effects of pecilocin can vary greatly depending on the dose, the individual's physiology, and the context in which it is taken. Common effects include changes in perception, mood, and thought. At higher doses, pecilocin can induce intense visual hallucinations and mystical experiences.

Legal Status[edit | edit source]

The legal status of pecilocin varies by country. In many places, it is classified as a Schedule I controlled substance, meaning it is illegal to manufacture, distribute, or possess. However, there are some exceptions for religious and scientific use.

See Also[edit | edit source]



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Contributors: Prab R. Tumpati, MD