Petrichloral

Petrichloral is a sedative and hypnotic drug. It is a derivative of chloral hydrate and is used for similar purposes. Petrichloral is less potent and slower to act than chloral hydrate, but is less toxic and less liable to cause dependence. It is also used in veterinary medicine.

Pharmacology

Petrichloral acts as a GABA_A receptor positive allosteric modulator. It has similar effects to those of barbiturates on the GABA_A receptor, but is less potent. Petrichloral also has weak anticholinergic effects.

Medical uses

Petrichloral is used as a sedative and hypnotic in the treatment of insomnia and other sleep disorders. It is also used in veterinary medicine for the sedation of animals.

Side effects

The most common side effects of petrichloral are drowsiness, dizziness, and nausea. Less common side effects include headache, confusion, and hallucinations. Rare but serious side effects include respiratory depression, liver damage, and dependence.

See also

• Chloral hydrate
• GABA_A receptor
• Insomnia

Petrichloral Resources
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