Phenolic

From WikiMD's Wellness Encyclopedia


Phenolics are a class of chemical compounds consisting of a hydroxyl group (-OH) bonded directly to an aromatic hydrocarbon group. The simplest of the class is phenol, which is also called carbolic acid C6H5OH. Phenolics are characterized by their strong antioxidant properties, which make them widely useful in the fields of medicine, food preservation, and the manufacture of various industrial products.

Properties and Structure[edit | edit source]

Phenolics possess at least one aromatic ring with one or more hydroxyl groups attached. The properties of phenolic compounds are largely determined by the structure of the phenol, and the nature and position of the substituents. Phenolic structures are classified into simple phenols or polyphenols based on the number of phenol units in the molecule.

Sources and Production[edit | edit source]

Phenolics are widely distributed in the plant kingdom. They are commonly found in both edible and inedible plants. Phenolics can be extracted from plants through various methods that may involve solvents, distillation, or pressing. Industrial synthesis of phenolics, like phenol itself, typically involves processes such as the cumene process, where benzene is alkylated with propylene to form cumene, which is then oxidized by air to produce phenol and acetone.

Applications[edit | edit source]

      1. In Medicine

Phenolics have a long history of use in medicine due to their antiseptic properties. They are used in the formulation of disinfectants and antiseptics. Additionally, their antioxidant properties make them valuable in the prevention and treatment of diseases related to oxidative stress.

      1. In Food Industry

In the food industry, phenolics are important as natural preservatives. They inhibit the oxidation of fats and other vulnerable components of food, thus extending shelf life. They also contribute to the flavor, color, and nutritional value of food.

      1. In Industrial Applications

Phenolics are used in the manufacture of a wide range of industrial products including plastics, explosives, and fibers. They are also used in the production of laminates, adhesives, and coatings.

Health Effects[edit | edit source]

While phenolics are beneficial in many ways, their high concentration, especially in certain industrial applications, can pose health risks such as skin irritation or respiratory problems. In food, however, they are generally regarded as safe and beneficial antioxidants.

Environmental Impact[edit | edit source]

Phenolics can also have environmental impacts. They are biodegradable to some extent, but their breakdown products can sometimes be more harmful than the original compounds. Therefore, their environmental release, particularly from industrial sources, must be managed to avoid pollution.

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Contributors: Prab R. Tumpati, MD