Phenothrin

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An article about the insecticide Phenothrin


Overview[edit | edit source]

Chemical structure of Phenothrin

Phenothrin, also known as Sumithrin, is a synthetic pyrethroid insecticide. It is commonly used in household insecticides and products for controlling lice and fleas on pets. Phenothrin is valued for its effectiveness in killing insects while being relatively safe for humans and pets when used as directed.

Chemical Properties[edit | edit source]

Phenothrin is a member of the pyrethroid family, which are synthetic analogs of the natural insecticide pyrethrin derived from chrysanthemum flowers. The chemical structure of Phenothrin includes a cyclopropane carboxylate ester, which is crucial for its insecticidal activity. It is a mixture of isomers, with the active isomer being responsible for its insecticidal properties.

Mechanism of Action[edit | edit source]

Phenothrin works by disrupting the normal function of the nervous system in insects. It affects the sodium channels in the nerve cells, leading to paralysis and eventual death of the insect. This mode of action is similar to that of other pyrethroids, making it effective against a wide range of insect pests.

Uses[edit | edit source]

Phenothrin is used in various applications, including:

  • Household insecticides: It is a common ingredient in sprays and foggers used to control mosquitoes, flies, and other household pests.
  • Pet care products: Phenothrin is used in shampoos and sprays to control fleas and ticks on dogs and cats.
  • Public health: It is employed in vector control programs to reduce the spread of diseases carried by insects, such as malaria and dengue fever.

Safety and Environmental Impact[edit | edit source]

While Phenothrin is considered safe for humans and pets when used according to label instructions, it can be toxic to aquatic life, particularly fish and amphibians. Therefore, care must be taken to prevent contamination of water bodies. It is also important to follow safety guidelines to minimize exposure to non-target organisms.

Regulation[edit | edit source]

Phenothrin is regulated by various governmental agencies, including the Environmental Protection Agency (EPA) in the United States, which sets guidelines for its use to ensure safety for humans and the environment.

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Contributors: Prab R. Tumpati, MD