Phosphorus-32
Phosphorus-32 (P-32) is a radioactive isotope of phosphorus. This isotope is a beta particle emitter with a half-life of 14.29 days. It is used in a variety of medical and scientific applications due to its radioactive properties.
Production[edit | edit source]
Phosphorus-32 is produced in a nuclear reactor by the neutron irradiation of phosphorus-31. The reaction is as follows:
P-31 + n → P-32
This reaction is an example of nuclear transmutation, where a neutron is absorbed by a nucleus, causing it to change into a different element or isotope.
Medical Uses[edit | edit source]
Phosphorus-32 is used in medicine for the treatment of certain types of cancer, such as polycythemia vera and chronic myeloid leukemia. It works by emitting beta particles that kill cancer cells. The isotope is usually administered orally or by injection.
In addition, P-32 is used in radiopharmaceuticals for the treatment of certain bone diseases, such as metastatic bone disease. The isotope is incorporated into the bone, where it emits beta particles that kill cancer cells.
Scientific Uses[edit | edit source]
In science, phosphorus-32 is used as a tracer in biochemical research. It is used to label phospholipids, nucleic acids, and other phosphorus-containing compounds. This allows scientists to track the movement and distribution of these compounds in biological systems.
Safety[edit | edit source]
Like all radioactive isotopes, phosphorus-32 poses a risk of radiation sickness if not handled properly. Therefore, it is important to follow all safety guidelines when working with this isotope.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD