Phytoene

From WikiMD's Food, Medicine & Wellness Encyclopedia

Phytoene is a 40-carbon intermediate in the biosynthesis of carotenoids. This colorless carotene is a product of the enzyme Phytoene synthase, and is converted into lycopene by the enzyme Phytoene desaturase.

Biosynthesis[edit | edit source]

The biosynthesis of phytoene is a part of the larger carotenoid biosynthesis pathway. The process begins with the condensation of two molecules of geranylgeranyl pyrophosphate (GGPP), a 20-carbon compound, to form the 40-carbon phytoene. This reaction is catalyzed by the enzyme Phytoene synthase.

Phytoene is then converted into lycopene through a series of desaturation and isomerization reactions. The first step in this process is the desaturation of phytoene to form phytofluene, a reaction catalyzed by the enzyme Phytoene desaturase. Further desaturation and isomerization reactions lead to the formation of lycopene.

Role in Plants[edit | edit source]

In plants, phytoene is a crucial intermediate in the biosynthesis of carotenoids, which are important for photosynthesis and for the protection of chloroplasts from photooxidative damage. Carotenoids also play a role in attracting pollinators and in seed dispersal by providing color to flowers and fruits.

Health Benefits[edit | edit source]

Phytoene, along with other carotenoids, has been associated with various health benefits in humans. It is an antioxidant, and it has been suggested to have anti-cancer properties. However, more research is needed to fully understand the potential health benefits of phytoene.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD