Pier Paolo Pandolfi

Pier Paolo Pandolfi 2017

Pier Paolo Pandolfi is an Italian-American cancer researcher and geneticist. He is known for his contributions to the understanding of the molecular mechanisms of cancer and the development of novel therapeutic strategies.

Early Life and Education

Pier Paolo Pandolfi was born in Italy. He completed his medical degree and Ph.D. in Italy before moving to the United States to further his research career.

Career

Pandolfi has held several prominent positions in the field of cancer research. He has worked at institutions such as the Memorial Sloan Kettering Cancer Center and the Beth Israel Deaconess Medical Center. He has also been a professor at Harvard Medical School.

Research Contributions

Pandolfi's research has significantly advanced the understanding of the genetic and molecular basis of cancer. His work has focused on the role of tumor suppressor genes and oncogenes in the development and progression of cancer. He has also explored the mechanisms of apoptosis and cell cycle regulation.

One of his notable contributions is the identification of the PML-RARα fusion protein, which is implicated in acute promyelocytic leukemia (APL). This discovery has led to the development of targeted therapies for APL, significantly improving patient outcomes.

Awards and Honors

Pandolfi has received numerous awards for his contributions to cancer research, including the Leukemia & Lymphoma Society Scholar Award and the American Italian Cancer Foundation Prize for Scientific Excellence in Medicine.

Personal Life

Pandolfi resides in the United States and continues to be actively involved in cancer research and education.

See Also

• Cancer research
• Genetics
• Tumor suppressor gene
• Oncogene
• Apoptosis
• Cell cycle