Pipemidic acid

Pipemidic acid is a type of antibiotic that belongs to the quinolone class. It is primarily used in the treatment of urinary tract infections caused by susceptible bacteria.

History

Pipemidic acid was first synthesized in the 1960s by the Japanese pharmaceutical company Taisho Pharmaceutical. It was one of the first quinolone antibiotics to be developed and has since been used in many countries around the world.

Medical uses

Pipemidic acid is used to treat urinary tract infections caused by susceptible bacteria. It works by inhibiting the DNA gyrase enzyme, which is necessary for bacterial DNA replication. This prevents the bacteria from multiplying and allows the body's immune system to eliminate the infection.

Side effects

Like all antibiotics, pipemidic acid can cause side effects. The most common side effects include nausea, vomiting, diarrhea, and abdominal pain. In rare cases, it can cause serious side effects such as allergic reactions, liver damage, and photosensitivity.

Pharmacology

Pipemidic acid works by inhibiting the DNA gyrase enzyme, which is necessary for bacterial DNA replication. This prevents the bacteria from multiplying and allows the body's immune system to eliminate the infection.

Society and culture

Pipemidic acid is available in many countries around the world. It is usually available as a prescription medication and is sold under various brand names.

See also

• Quinolone
• Urinary tract infection
• DNA gyrase

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