Pirenoxine

Pirenoxine

Pirenoxine (also known as Catalin) is a pyridine derivative used in the treatment of cataracts. It is often used in the form of eye drops and is known to prevent the formation of sulphur compounds that cloud the eye lens.

Chemistry

Pirenoxine is a chemical compound with the formula C16H12N2O3. It belongs to the class of organic compounds known as pyridines and derivatives. These are compounds containing a pyridine ring, which is a six-membered aromatic ring with one nitrogen atom.

Pharmacology

Pirenoxine works by chelating the calcium ions present in the aqueous humour of the eye. This prevents the formation of insoluble calcium salts, which can cloud the lens and lead to cataracts. It also inhibits the oxidation of glutathione, an important antioxidant in the eye.

Clinical Use

Pirenoxine is used in the treatment of cataracts. It is often administered in the form of eye drops, which are applied directly to the eye. The typical dosage is one to two drops, three to four times a day. Treatment duration varies depending on the severity of the cataracts, but it is generally recommended to continue treatment for at least three months.

Side Effects

Like all medications, Pirenoxine can cause side effects. The most common side effects include eye irritation, redness, and sensitivity to light. In rare cases, it can cause allergic reactions, such as rash, itching, and swelling of the eye or eyelid.

See Also

• Cataracts
• Pyridines
• Calcium