Pitofenone

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Pitofenone


Pitofenone is a spasmolytic agent, a type of medication used to relieve spasm of smooth muscle. It is often combined with other drugs in the treatment of various medical conditions.

Pharmacology[edit | edit source]

Pitofenone acts by reducing the tone of smooth muscle in the body. It does this by blocking the action of acetylcholine, a neurotransmitter that is responsible for transmitting signals in the nervous system. This results in a decrease in the contractions of the smooth muscle, thereby relieving spasms.

Medical Uses[edit | edit source]

Pitofenone is used in combination with other drugs such as fenpiverinium bromide and metamizole in the treatment of conditions such as gastrointestinal spasm, biliary colic, and renal colic. It is also used in the treatment of postoperative pain and other conditions associated with smooth muscle spasm.

Side Effects[edit | edit source]

Like all medications, pitofenone can cause side effects. These may include dry mouth, blurred vision, urinary retention, and constipation. In rare cases, it can cause severe allergic reactions.

Contraindications[edit | edit source]

Pitofenone is contraindicated in patients with myasthenia gravis, a condition that causes muscle weakness. It is also contraindicated in patients with glaucoma, a condition that increases pressure in the eye, and in patients with prostatic hypertrophy, an enlargement of the prostate gland.

Interactions[edit | edit source]

Pitofenone may interact with other medications, including other spasmolytics, anticholinergic drugs, and antidepressants. It is important for patients to inform their healthcare provider of all medications they are currently taking.

See Also[edit | edit source]

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