Plasma frozen within 24 hours after phlebotomy

Plasma frozen within 24 hours after phlebotomy (FP24) is a type of blood plasma product used in medicine and transfusion medicine for a variety of therapeutic and medical purposes. This plasma is collected from a donor through the process of phlebotomy and is then frozen within 24 hours to preserve its function and integrity. The rapid freezing process is crucial for maintaining the quality and effectiveness of the plasma for transfusion.

Collection and Processing

The collection of plasma involves drawing blood from a donor, a process known as phlebotomy. Once collected, the blood is then separated into its components, typically using a centrifuge. The plasma, which is the liquid part of the blood containing water, salts, enzymes, antibodies, and other proteins, is extracted and then frozen within 24 hours of collection. This quick freezing process helps in preserving the essential proteins, especially the clotting factors, which are critical for many therapeutic uses.

Uses

FP24 is used in a variety of clinical settings. It is often administered to patients who need clotting factors, such as those with hemophilia or other bleeding disorders. It is also used in the treatment of patients with liver diseases, where the production of clotting factors is impaired, or in cases of massive transfusion where blood loss needs to be quickly replaced. Additionally, FP24 can be used in the treatment of certain immune deficiencies, as it contains antibodies that can help boost the patient's immune system.

Advantages

The primary advantage of using FP24 is its high quality and preserved functionality, especially regarding clotting factors and antibodies. Freezing plasma within 24 hours of collection maximizes the preservation of these proteins, making FP24 more effective for transfusion purposes compared to plasma that is frozen later. This quick freezing process helps ensure that the plasma retains its therapeutic properties, making it a critical resource in emergency and surgical settings.

Storage and Shelf Life

Once frozen, FP24 can be stored for an extended period, typically up to one year, without significant degradation of its components. This long shelf life allows for a readily available supply of plasma for transfusions, making it an essential component of blood banks and hospitals' inventory.

Safety and Screening

Like all blood products, FP24 undergoes rigorous testing and screening for infectious agents such as HIV, hepatitis B, and hepatitis C to ensure its safety for transfusion. Donors are carefully screened for risk factors and infectious diseases before donation, and the collected plasma is tested to meet strict safety standards.

Conclusion

Plasma frozen within 24 hours after phlebotomy is a vital blood product with a wide range of medical and therapeutic uses. Its rapid processing and freezing ensure the preservation of important proteins, making it an essential component in the treatment of various conditions. As with all blood products, the safety and efficacy of FP24 depend on strict adherence to collection, processing, and storage protocols.