Pneumocystis carinii

Pneumocystis carinii is a fungus species that is known to cause Pneumocystis pneumonia (PCP), a severe lung infection, especially in individuals with weakened immune systems.

Overview

Pneumocystis carinii was first identified in the early 20th century and was initially believed to be a protozoa. However, later research revealed that it is a fungus. It is one of several species in the genus Pneumocystis that can infect humans, with Pneumocystis jirovecii being the most common.

Infection and Disease

Infection with Pneumocystis carinii typically occurs in individuals with compromised immune systems, such as those with HIV/AIDS, those undergoing chemotherapy, or organ transplant recipients. The fungus is believed to be transmitted through the air and can cause a form of pneumonia known as Pneumocystis pneumonia.

Diagnosis and Treatment

Diagnosis of Pneumocystis carinii infection is typically made through examination of a sputum sample under a microscope. Treatment usually involves a combination of antibiotics and antifungal medications, such as trimethoprim-sulfamethoxazole.

See Also

• Pneumocystis jirovecii
• Pneumocystis pneumonia
• HIV/AIDS
• Immunosuppression