Pompholyx

From WikiMD's Food, Medicine & Wellness Encyclopedia

Pompholyx (also known as dyshidrotic eczema or dyshidrosis) is a type of eczema that is characterized by small blisters on the hands and feet. The condition is known for its itchy and fluid-filled blisters which can cause significant discomfort and sometimes pain. The exact cause of pompholyx is unknown, but it is believed to be related to a combination of genetic and environmental factors.

Symptoms[edit | edit source]

The primary symptoms of pompholyx include the sudden onset of blister formation on the palms of the hands, sides of the fingers, and soles of the feet. These blisters are often itchy and can become painful. After a period, the blisters may dry and peel, potentially leading to cracks and fissures in the skin. In severe cases, the blisters can become infected, requiring medical intervention.

Causes[edit | edit source]

While the exact cause of pompholyx is not fully understood, several factors are believed to contribute to its development. These include:

  • Stress: Emotional stress is considered a common trigger for pompholyx outbreaks.
  • Allergies: Some individuals may develop pompholyx as a reaction to certain allergens.
  • Sweating: Excessive sweating or hyperhidrosis can exacerbate the condition.
  • Irritants: Exposure to certain irritants such as nickel, cobalt, or chromium can trigger pompholyx in susceptible individuals.

Diagnosis[edit | edit source]

Diagnosis of pompholyx is primarily based on the clinical presentation of the blisters and the history of the patient. In some cases, patch testing may be conducted to rule out allergic contact dermatitis. Additionally, fungal cultures may be taken to exclude fungal infections, which can present similarly.

Treatment[edit | edit source]

Treatment for pompholyx aims to relieve symptoms and prevent new blisters from forming. Common treatment options include:

  • Topical corticosteroids: These are applied to the affected areas to reduce inflammation and itching.
  • Moisturizers: Regular use of moisturizers can help repair the skin barrier and prevent dryness.
  • Antihistamines: These may be prescribed to reduce itching, especially at night.
  • Phototherapy: Exposure to ultraviolet light under medical supervision can help in severe cases.

In cases where secondary infection is present, antibiotics may be prescribed. It is also important for individuals with pompholyx to identify and avoid potential triggers.

Prevention[edit | edit source]

Preventative measures for pompholyx include avoiding known irritants, managing stress, and maintaining good hand and foot hygiene. Wearing gloves when handling irritants and avoiding excessive sweating can also help prevent outbreaks.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD