Pranlukast

Pranlukast is a leukotriene receptor antagonist and mast cell stabilizer that is used in the treatment of asthma and allergic rhinitis. It is marketed in Japan and South Korea.

Mechanism of Action[edit | edit source]

Pranlukast inhibits the effects of leukotrienes D4 and E4 on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to them, which reduces the bronchoconstrictive activities, such as the inflammation and edema of the respiratory mucosa, eosinophil infiltration, and stimulation of mucus secretion.

Medical Uses[edit | edit source]

Pranlukast is used for the treatment of bronchial asthma, allergic rhinitis, and urticaria. It is also used for the prevention of asthma attacks.

Side Effects[edit | edit source]

Common side effects of Pranlukast include nausea, diarrhea, stomach pain, liver problems, and hypersensitivity reactions.

Interactions[edit | edit source]

Pranlukast may interact with other drugs such as warfarin, theophylline, and erythromycin.

See Also[edit | edit source]

Pranlukast Resources
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