Montelukast
Montelukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma. It is marketed as Singulair.
Information about Montelukast[edit source]
Montelukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma.
Liver safety of Montelukast[edit source]
It has been linked to rare cases of clinically apparent liver injury.
Mechanism of action of Montelukast[edit source]
Montelukast (mon" te loo' kast) is a leukotriene receptor antagonist that binds to the CysLT1 and CysLT2 receptors, thereby interfering with inflammatory pathways that are involved in the pathogenesis of asthma and allergic rhinitis. Montelukast has been shown to reduce symptoms of asthma and allergic rhinitis and prevent acute attacks.
FDA approval information for Montelukast[edit source]
Montelukast was approved for use in the United States in 1998 and is widely used with more than 20 million prescriptions being filled yearly. Current indications for montelukast include prophylaxis and chronic treatment of asthma, prevention of exercise induced bronchoconstriction and allergic rhinitis.
Dosage and administration for Montelukast[edit source]
Montelukast is available in several generic forms and under the commercial name Singulair. The recommended dosage for adults is 10 mg once daily. Lower doses and chewable tablets are recommended for pediatric patients.
Side effects of Montelukast[edit source]
Common side effects include dyspepsia, abdominal discomfort, asthenia, headache, dizziness, fatigue and fever.
| Montelukast Resources | |
|---|---|
|
 |
Albuterol, Bitolterol, Formoterol, Metaproterenol, Pirbuterol, Salbutamol, Salmeterol, Terbutaline
Leukotriene Receptor Antagonists
Benralizumab, Mepolizumab, Omalizumab, Reslizumab
| Montelukast Resources | |
|---|---|
|
|
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
