Etalocib
Etalocib is a drug that was under development for the treatment of cancer. It was being developed by Eli Lilly and Company and was in Phase II clinical trials when development was discontinued.
Mechanism of Action[edit | edit source]
Etalocib is a selective inhibitor of the enzyme COX-2. COX-2 is an enzyme that is often overexpressed in cancer cells, leading to increased production of prostaglandins that promote tumor growth and angiogenesis. By inhibiting COX-2, etalocib was intended to slow or stop the growth of cancer cells.
Clinical Trials[edit | edit source]
Etalocib was in Phase II clinical trials for the treatment of colorectal cancer and non-small cell lung cancer. However, the development of the drug was discontinued due to lack of efficacy.
Side Effects[edit | edit source]
The most common side effects reported in clinical trials were nausea, vomiting, and diarrhea. Other side effects included fatigue, anemia, and neutropenia.
See Also[edit | edit source]
- Cancer
- COX-2
- Prostaglandins
- Tumor growth
- Angiogenesis
- Colorectal cancer
- Non-small cell lung cancer
- Nausea
- Vomiting
- Diarrhea
- Fatigue
- Anemia
- Neutropenia
Etalocib Resources | ||
---|---|---|
|
|
|
Find a healthcare provider anywhere in the world quickly and easily!
Translate to: East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski
WikiMD is the world's largest, free medical and wellness encyclopedia edited only by professionals. Advertise!
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD