Tipelukast
A leukotriene receptor antagonist used in the treatment of asthma and allergic rhinitis
| Tipelukast | |
|---|---|
| |
| INN | |
| Drug class | |
| Routes of administration | |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Legal status | |
| CAS Number | |
| PubChem | |
| DrugBank | |
| ChemSpider | |
| KEGG | |
Tipelukast is a leukotriene receptor antagonist (LTRA) used primarily in the management of asthma and allergic rhinitis. It functions by blocking the action of leukotrienes, which are inflammatory chemicals the body releases after coming in contact with an allergen or irritant.
Mechanism of Action[edit | edit source]
Tipelukast works by inhibiting the cysteinyl leukotriene receptor, specifically the CysLT1 receptor. Leukotrienes are produced by the immune system and contribute to inflammation, bronchoconstriction, and mucus production in the airways. By blocking these receptors, tipelukast helps to reduce inflammation and relax the airways, making it easier to breathe.
Clinical Uses[edit | edit source]
Tipelukast is primarily used in the treatment of chronic asthma and to relieve symptoms of allergic rhinitis. It is not intended for the relief of acute asthma attacks but is used as a maintenance therapy to prevent symptoms.
Asthma[edit | edit source]
In patients with asthma, tipelukast helps to prevent wheezing, difficulty breathing, and chest tightness. It is often used as an adjunct therapy in patients whose symptoms are not adequately controlled with inhaled corticosteroids.
Allergic Rhinitis[edit | edit source]
For allergic rhinitis, tipelukast helps to alleviate symptoms such as nasal congestion, runny nose, and sneezing. It is particularly useful in patients who have both asthma and allergic rhinitis, providing a dual benefit.
Side Effects[edit | edit source]
Common side effects of tipelukast include headache, dizziness, and gastrointestinal disturbances such as nausea and diarrhea. Rarely, it may cause mood changes or allergic reactions.
Administration[edit | edit source]
Tipelukast is administered orally, usually once daily. The dosage may vary based on the patient's age, weight, and severity of symptoms.
Related pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
