Carpipramine

Carpipramine is a type of antipsychotic medication, specifically a tricyclic antidepressant (TCA), that is primarily used in the treatment of schizophrenia and other psychotic disorders. It was first developed in the 1970s by the Japanese pharmaceutical company Dainippon Sumitomo Pharma.

Pharmacology

Carpipramine acts as an antagonist at certain types of dopamine receptors, specifically the D2 and D3 subtypes. This action is believed to be responsible for its antipsychotic effects. It also has some affinity for the serotonin 5-HT2A receptor, which may contribute to its antidepressant effects.

Clinical Use

Carpipramine is used primarily in the treatment of schizophrenia, a chronic and severe mental disorder that affects how a person thinks, feels, and behaves. It may also be used in the treatment of other psychotic disorders, such as bipolar disorder and major depressive disorder with psychotic features.

Side Effects

Like all medications, carpipramine can cause side effects. Common side effects include drowsiness, dizziness, dry mouth, and constipation. Less common but more serious side effects can include tardive dyskinesia (a movement disorder), neuroleptic malignant syndrome (a potentially life-threatening reaction to antipsychotic drugs), and cardiac arrhythmias.

See Also

• Antipsychotic
• Schizophrenia
• Tricyclic antidepressant
• Dopamine receptor
• Serotonin