Primary interatrial foramen
Primary Interatrial Foramen[edit | edit source]
The Primary Interatrial Foramen is a crucial structure in the embryonic heart that allows the flow of blood between the left and right atria before the formation of the foramen ovale.
Development[edit | edit source]
During the embryonic development of the heart, the primary interatrial foramen forms as a result of the degradation of the dorsal part of the septum primum. This degradation is necessary to maintain the connection between the left and right atria after the septum primum begins to close the interatrial septum.
Function[edit | edit source]
The primary function of the primary interatrial foramen is to allow the flow of oxygenated blood from the right atrium to the left atrium. This is crucial during fetal development as the lungs are not yet functional and the fetus relies on the mother's oxygen supply.
Closure[edit | edit source]
The primary interatrial foramen closes shortly after birth when the lungs become functional and the foramen ovale closes. This closure prevents the mixing of oxygenated and deoxygenated blood in the heart, allowing for efficient oxygen delivery to the body's tissues.
Clinical Significance[edit | edit source]
If the primary interatrial foramen fails to close after birth, it can result in a condition known as patent foramen ovale. This can lead to a number of health issues, including stroke and heart failure.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
