Proscaline

Proscaline is a psychedelic phenethylamine of the 2C family. It is closely related to mescaline and was first synthesized by Alexander Shulgin.

History

Proscaline was first synthesized and investigated by Alexander Shulgin. In his book PiHKAL, Shulgin lists the dosage range as 30 to 60 mg, consumed orally. The duration of proscaline is noted to be 8 to 12 hours.

Chemistry

Proscaline is a phenethylamine with a propyl group on the amine. It is structurally similar to mescaline, but has a three-carbon chain rather than a three-carbon ring.

Pharmacology

Like other psychedelic phenethylamines, proscaline likely acts as a 5-HT2A receptor agonist. However, the exact mechanism of action is not fully understood.

Effects

The effects of proscaline are similar to those of other psychedelic phenethylamines. These can include hallucinations, altered thinking processes, closed and open eye visuals, synesthesia, an altered sense of time, and spiritual experiences. The effects are often described as being similar to those of mescaline, though with a significantly different duration and intensity.

Legal status

The legal status of proscaline varies by country. In the United States, it is not specifically listed as a controlled substance, but it may be considered an analog of a controlled substance under the Federal Analogue Act.

See also

• Phenethylamine
• Psychedelic drug
• PiHKAL
• Alexander Shulgin