Clidinium bromide
(Redirected from Quarzan)
An anticholinergic drug used to treat peptic ulcers and other gastrointestinal disorders
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Clidinium bromide is an anticholinergic drug that is used in combination with other medications to treat peptic ulcers and other gastrointestinal disorders. It is often combined with chlordiazepoxide in a formulation known as Librax.
Pharmacology[edit | edit source]
Clidinium bromide works by reducing the secretions of certain organs in the body. It is an anticholinergic agent, which means it blocks the action of the neurotransmitter acetylcholine in the central nervous system and peripheral nervous system. This action helps to decrease the muscle spasms in the gastrointestinal tract and reduce the production of stomach acid.
Medical uses[edit | edit source]
Clidinium bromide is primarily used to treat:
Side effects[edit | edit source]
Common side effects of clidinium bromide include:
Less common side effects may include:
Contraindications[edit | edit source]
Clidinium bromide should not be used in individuals with:
Mechanism of action[edit | edit source]
Clidinium bromide exerts its effects by blocking the muscarinic acetylcholine receptors in the smooth muscle of the gastrointestinal tract. This leads to a reduction in muscle spasms and a decrease in the secretion of stomach acids.
History[edit | edit source]
Clidinium bromide was first introduced in the 1960s and has been used in combination with other medications to treat various gastrointestinal disorders. Its combination with chlordiazepoxide, a benzodiazepine, is particularly popular for its dual action of reducing anxiety and gastrointestinal symptoms.
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