RNASE6
RNASE6 or Ribonuclease A Family Member k6 is a protein that in humans is encoded by the RNASE6 gene. It is a member of the ribonuclease A superfamily, which is a group of enzymes that degrade RNA.
Function[edit | edit source]
The RNASE6 protein is a secreted ribonuclease, which means it is released from the cell to perform its function. It is believed to be involved in the immune response by degrading specific RNA molecules of pathogens and modulating the activity of immune cells.
Gene[edit | edit source]
The RNASE6 gene is located on the short (p) arm of chromosome 14 at position 24.3, from base pair 67,074,879 to base pair 67,078,879.
Clinical significance[edit | edit source]
Alterations in the RNASE6 gene have been associated with various diseases. For example, a higher expression of RNASE6 has been found in patients with rheumatoid arthritis and lupus erythematosus. However, the exact role of RNASE6 in these diseases is still under investigation.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
- RNASE6 at the National Center for Biotechnology Information
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