Rafoxanide

Rafoxanide

Rafoxanide is a salicylanilide anthelmintic and antiparasitic drug used in veterinary medicine. It is used primarily for the treatment of parasitic infections in livestock, particularly those caused by flukes and nematodes.

Chemistry

Rafoxanide is a member of the salicylanilide class of anthelmintics. It is a synthetic compound, derived from salicylic acid and aniline. The chemical structure of rafoxanide includes a phenyl ring and a carboxylic acid group, which are characteristic of the salicylanilide class.

Mechanism of Action

The exact mechanism of action of rafoxanide is not fully understood. However, it is believed to work by inhibiting the enzymes of the parasites, thereby disrupting their metabolic processes. This leads to the death of the parasites.

Uses

Rafoxanide is used in veterinary medicine for the treatment of parasitic infections in livestock. It is effective against a wide range of parasites, including flukes and nematodes. It is also used in the treatment of fascioliasis, a parasitic infection caused by the liver fluke.

Side Effects

Like all drugs, rafoxanide can cause side effects. These may include allergic reactions, nausea, vomiting, and diarrhea. In rare cases, it can cause serious side effects such as liver damage or neurological disorders.

Regulation

In many countries, the use of rafoxanide is regulated by the veterinary medicines authority. It is usually available only on prescription from a veterinarian.

See Also

• Salicylanilide
• Anthelmintic
• Antiparasitic
• Veterinary Medicine