Ricasetron
Ricasetron is a drug that belongs to the class of 5-HT3 antagonists. It is primarily used in the treatment of chemotherapy-induced nausea and vomiting (CINV). Ricasetron works by blocking the action of serotonin, a natural substance in the brain that can cause vomiting.
Pharmacology[edit | edit source]
Ricasetron is a potent and selective antagonist of the 5-HT3 receptor, a type of serotonin receptor that is found predominantly in the central nervous system and in the gastrointestinal tract. By blocking these receptors, Ricasetron prevents the activation of the vomiting reflex by serotonin, which is released in large amounts during chemotherapy.
Clinical Use[edit | edit source]
Ricasetron is used in the prevention and treatment of acute and delayed nausea and vomiting associated with chemotherapy. It is usually administered orally or intravenously before the start of chemotherapy. Ricasetron has been shown to be effective in reducing the severity of CINV and improving the quality of life of cancer patients.
Side Effects[edit | edit source]
Common side effects of Ricasetron include headache, constipation, and fatigue. Less common side effects include dizziness, diarrhea, and abdominal pain. As with all drugs, the potential benefits of Ricasetron should be weighed against its potential risks before use.
See Also[edit | edit source]
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