Ro 3-0419
Ro 3-0419 is a highly toxic organophosphate acetylcholinesterase inhibitor.
Structure[edit | edit source]
It is the neutral analog of Ro 3-0422.
Features[edit | edit source]
Although Ro 3-0419 is less potent than Ro 3-0422, it does not have a positively charged nitrogen atom, resulting in its ability to cross the blood brain barrier to inhibit cholinesterases in the brain.
Lethal dose[edit | edit source]
The intravenous LD50 of Ro 3-0419 is 1 mg/kg in mice.
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