Robenidine

Robenidine

Robenidine is a chemical compound used as an antiprotozoal agent, primarily in veterinary medicine. It is commonly employed to prevent and treat coccidiosis in poultry and other livestock. Robenidine is known for its efficacy against various species of Eimeria, the protozoan parasites responsible for coccidiosis.

Chemical Properties

Robenidine is a member of the guanidine class of compounds. Its chemical structure includes a guanidine moiety, which is essential for its antiprotozoal activity. The compound is typically administered in the form of its hydrochloride salt, known as robenidine hydrochloride.

Mechanism of Action

Robenidine works by interfering with the energy metabolism of Eimeria species. It disrupts the mitochondrial function of the parasites, leading to their death. This action helps in controlling the spread of coccidiosis in infected animals.

Usage in Veterinary Medicine

Robenidine is primarily used in the poultry industry to control coccidiosis. It is often added to feed or drinking water to ensure that the animals receive a consistent dose. The compound is effective against multiple stages of the Eimeria life cycle, making it a versatile option for coccidiosis management.

Safety and Toxicity

While robenidine is generally considered safe for use in animals, it is important to adhere to recommended dosages to avoid potential toxicity. Overdosage can lead to adverse effects, including reduced feed intake and growth rates in poultry. It is also crucial to observe withdrawal periods before slaughter to ensure that residues do not remain in the meat.

Regulation and Approval

Robenidine is approved for use in many countries, subject to regulatory guidelines. It is important for veterinarians and farmers to follow local regulations regarding its use to ensure both efficacy and safety.

Related Pages

• Coccidiosis
• Eimeria
• Antiprotozoal
• Poultry farming
• Veterinary medicine